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Question: Is the canvas sticky, or do I have to apply glue to each diamond?
Answer: The diamond canvas has a sticky surface that keeps the beads strong and won't fall off easily. If youâre not finished but need to quit, Keep the plastic cover on it at all times. Just pull it away on the section youâre working on."p" "p""b"Question: What size picture frame did everyone get for theirs? "p""b"Answer: The canvas size of our diamond painting kit is 11.8x15.8In (30X40CM). The pattern size is 9.5x13.4In (24X34CM). When choosing a frame, it is recommended that the internal size of the frame is at least 9.5x13.4In(24X34CM) "p""br" "p" "p""b"DIY STEPS: "p"1. refer to the comparison table on the canvas to identify each diamond number and the corresponding printed number on the canvas. "p"2. Insert the round end of the dotting pen into the dotting cement (push hard to keep the cement in place). "p"3. Use the round end of the pen to stick a diamond and slightly press down to remove any extra cement. "p"4. Tear apart the partial film and place the diamond on the canvas according to the corresponding number. "p"5.If you stick a diamond to the wrong area on the painting, remove the diamond with tweezers. "p"6. After finishing, slightly press down the diamonds with your hand or a book to ensure that the diamonds are firmly attached. "p""br" "p" "p""b"Note: "p"1. Please do not let children play to avoid accidents such as swallowing. "p"2. Please do not pull the transparent protective film on the canvas one time. Tear apart half of it to protect the glue from losing viscous. "p"3. The product did not include the frame. It is just a rolled canvas. Please frame it with glasses or wooden and hang it in your home as for decoration adornments. "p"4. Due to the different monitor and light effects, the actual color of the item might be slightly different from the color showed in the pictures.
Molecular pathway of estrogen receptor (ER) action. Typically, estrogen binds to the ligand-binding domain of receptors in the nucleus, which causes a conformational change. Estrogen-responsive elements (ERE) mediate genomic effects. RE, response element; TF, transcription factor; GF, growth factor; GF-R, growth factor receptor; CoA, co-activator; CoR, co-repressor; MAPK, mictogen-activated protein kinase; PI3K, phophoinositide 3-kinase; Src, proto-oncogene tyrosine-protein kinase; AP-1, activating protein-1; Sp-1, stimulating protein-1. Adapted from Nie et al.16
Measurement parameters utilized to determine the esophageal motor function. (A) Esophagogastric junction (EGJ). (B) Esophageal body. EGJ-CI, esophagogastric junction-contractile integral; IRP, integrated relaxation pressure; LES, lower esophageal sphincter.
High-resolution manometry test swallows and maneuvers. (A) Supine 5 mL liquid; (B) upright 5 mL liquid; (C) viscous (apple sauce); (D) solid (graham cracker); (E) multiple rapid swallow; and (F) rapid drink challenge. Integrated relaxation pressure (IRP) and distal contractile integral (DCI) were 11 mmHg and 1760 mmHg·cm·sec (A), 8 mmHg and 1950 mmHg·cm·sec (B), 7 mmHg and 1600 mmHg·cm·sec (C), 10 mmHg and 1400 mmHg·cm·sec (D), 4 mmHg and 4600 mmHg·cm·sec (E), and 3 mmHg and 0 mmHg·cm·sec (F), respectively. Figure used with permission from the Esophageal Center at Northwestern.
Our diagnostic algorithm of defecation disorders using a colonic transit study. DD, defecation disorders; DRE, digital rectal examination; NTC, normal transit constipation; STC, slow transit constipation; RS, rectosigmoid colon.
Statistical maps showing voxel-mirrored homotopic connectivity (VMHC) differences between irritable bowel syndrome (IBS) and healthy controls (HCs;